Honestly, with 4.10 gears, and pulling a 5th wheel, you're pretty much in the ballpark with 9 to 11 MPG
The weight is a big issue, but the wind resistence is another major factor (especially as you increase speed)
Does your truck have 4" exhaust all the way back? if not, opening it up may help a little bit
Just running your Smarty with wild timing (keep everything else fairly mild) will help too